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Gregorio Valdez, PhD

GLF Translational Associate Professor of Molecular Biology, Cell Biology and Biochemistry
Brown University
Providence, Rhode Island, United States

I earned a B.S. degree in Biochemistry from Lehman College in 1996, and a Ph.D. in 2005 from Stony Brook University under the mentorship of Dr. Simon Halegoua, followed by postdoctoral research at Harvard University in the laboratory of Dr. Joshua Sanes. In 2012, I accepted a position as Assistant Professor at Virginia Polytechnic Institute (Virginia Tech). In 2019, I moved to Brown University to join the Department of Molecular Biology, Cell Biology and Biochemistry in the Division of Biology and Medicine, and the Center for Translational Neuroscience. My research is primarily focused on discovering molecules that function to preserve and restore the function of the nervous system and skeletal muscles during normal aging and affected with age-related diseases. Over the years, I have identified molecules that function to slow degeneration of the synapse motor neurons and skeletal muscles form, called the neuromuscular junction (NMJ) during aging as well as in amyotrophic lateral sclerosis (ALS), an age-associated disease. I have also co-discovered molecules important for the formation and maintenance of brain synapses. In all, my scientific contributions have implications for mitigating the negative health effects of normal aging and treating age-related neurological diseases such as ALS and Alzheimer’s disease.

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