Reproductive Aging

Friday, November 10, 2023

10:00 AM – 11:30 AM ET

Location: Room 118

Chair(s)

Yousin Suh, PhD (she/her/hers)

Professor
Reproductive Sciences
Columbia University
New York City, New York, United States

Individual Symposium Abstract First Author(s)

Yousin Suh, PhD (she/her/hers)

Professor
Reproductive Sciences
Columbia University
New York City, New York, United States
Jennifer Garrison, PhD (she/her/hers)

Assistant Professor
Buck Institute
Novato, California, United States

Slides
Francesca Duncan, PhD (she/her/hers)

Associate Professor
Department of Obstetrics and Gynecology
Feinberg School of Medicine, Northwestern University
Chicago, Illinois, United States
Anna Murray, BSc, PhD

Professor of Human Genetics
University of Exeter
Exeter, England, United Kingdom

Reproductive aging is a major health, personal and societal issue, but ovarian aging has received limited scientific attention. Ovarian aging has been known to influence diverse health outcomes in women including lifespan, cardiovascular disease, metabolic syndromes, neurodegenerative disorders and various types of cancer. Yet, the mechanisms behind this broad implication remain elusive. This session will explore recent insights into the molecular, cellular and genetic basis of ovarian aging and new intervention targets to maintain reproductive health and later health outcomes in our aging female population.

Target audience:

This inter-disciplinary session is designed to educate basic scientists, physician-scientists, clinicians, and a general interest audience of providers or industry representatives interested in understanding the mechanisms of ovarian aging and its sequalae.

Learning Objectives:

At the conclusion of the session, attendees will be able to describe the "Hallmarks of Ovarian Aging" and unified mechanisms driving both reproductive and organismal aging.
Attendees will further be able to explain how the ovarian microenvironment and macroenvironment contribute to ovarian aging
Attendees will learn potential of known geroprotectors in delaying ovarian aging, thereby promoting women’s health.

Presentations:

10:00 AM – 11:30 AM ET

Ovarian Aging: A Target for Geroprotection in Women
Individual Symposium Abstract First Author: Yousin Suh, PhD (she/her/hers) – Columbia University
10:00 AM – 11:30 AM ET

Reframing Health and Aging through the Lens of Reproductive Longevity
Individual Symposium Abstract First Author: Jennifer Garrison, PhD (she/her/hers) – Buck Institute
10:00 AM – 11:30 AM ET

Modulating and Measuring the Ovarian Microenvironment to Improve Female Health-Span
Individual Symposium Abstract First Author: Francesca E. Duncan, PhD (she/her/hers) – Feinberg School of Medicine, Northwestern University
10:00 AM – 11:30 AM ET

Genomic Architecture of Female Reproductive Aging
Individual Symposium Abstract First Author: Anna Murray, BSc, PhD – University of Exeter