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Biological Sciences Invited Symposium

Biological Sciences

Presidential Symposium: Extending Healthspan and Longevity

Thursday, November 9, 2023
8:00 AM – 9:30 AM ET
Location: Room 118

    Chair(s)

  • Blanka Rogina, PhD, M.S. (she/her/hers)

    Professor
    Department of Genetics & Genome Sciences
    UConn Health
    Farmington, Connecticut, United States

    Slides

    • Co-Chair(s)

  • Rafael de Cabo, PhD

    Senior Investigator
    Translational Gerontology Branch
    National Institute on Aging
    Baltimore, Maryland, United States

    • Individual Symposium Abstract First Author(s)

  • Rafael de Cabo, PhD

    Senior Investigator
    Translational Gerontology Branch
    National Institute on Aging
    Baltimore, Maryland, United States

  • AG

    Ana Gomes, PhD

    Principal Investigator
    Department of Molecular Oncology
    Moffitt Cancer Center
    Tampa, Florida, United States

    Slides

  • Vishwa Dixit, DVM, PhD (he/him/his)

    Director, Yale Center for Research on Aging (Y-Age)
    Yale University
    New Haven, Connecticut, United States

  • PS

    Payel Sen, PhD

    Stadtman Tenure-track Investigator
    Laboratory of Genetics and Genomics
    National Institute on Aging, NIH
    Baltimore, Maryland, United States

Aging is associated with a functional decline in physiological, metabolic, proliferative, and tissue homeostasis leading to deterioration at an organismal level and an increase in risk for disease and death. To prevent or postpone such deterioration, genetic, pharmacological, and nutritional interventions have been successfully utilized, which lead to preserved healthspan and extended longevity. This symposium will discuss new approaches to target aging and the mechanisms underlying interventions that extend healthspan and longevity. The speakers of this symposium include internationally distinguished aging researchers who have dedicated their research to reveal new approaches to extending healthy lifespan. Rafael de Cabo, from NIA, Co-Chair and speaker in this symposium, will talk about the effects of calorie restriction on physiology, metabolism and health in a variety of organisms. Ana Gomes, from Moffitt Cancer Center, will talk about how aging promotes cancer resistance to therapy. Vishwa Deep Dixit, from Yale University, will discuss immunometabolic checkpoints of aging and lessons learned from CALERIE studies in humans. Payel Sen, from NIA, will present her studies on epigenetic mechanisms underlying tissue aging.

Learning Objectives:

  • After attending this session, participants will be able to better understand new findings in health span and longevity extension.
  • After attending this session, participants will learn about new and innovative approaches to extend healthspan and longevity.

Presentations:

  • 8:00 AM – 9:30 AM ET
    Prolonged Daily Fasting Times are Best when Combined with Calorie Restriction for Health and Survival

    Individual Symposium Abstract First Author: Rafael de Cabo, PhD – National Institute on Aging

  • 8:00 AM – 9:30 AM ET
    Age-Induced Systemic Reprogramming Drives Drug Resistance in Lung Cancer

    Individual Symposium Abstract First Author: Ana Gomes, PhD – Moffitt Cancer Center

  • 8:00 AM – 9:30 AM ET
    Immunometabolic Checkpoints of Inflammaging

    Individual Symposium Abstract First Author: Vishwa Deep Dixit, DVM, PhD (he/him/his) – Yale University

  • 8:00 AM – 9:30 AM ET
    Epigenetic Mechanisms of Tissue Aging

    Individual Symposium Abstract First Author: Payel Sen, PhD – National Institute on Aging, NIH